We study systems whose free energy landscape is complex in the sense that there are multiple minima, separated by large free energy barriers. Such systems are encontered in:

Material Science, for instance spin glasses, for which our work is summarized here.
- Picture show of Spin Glass Realizations
Biophysics, in particular for protein folding.
For our work see the paper with Meirovitch et al. from the publication list (pdf file).
Optimization, classical is the Traveling Salesman Problem (TSP).